New Funding Opportunity

The Pathways for Health Research Collective is seeking bold, rigorous projects that can improve health in the real world.

This new funding opportunity aims to support projects that would use existing evidence from health solutions science to improve health in a measurable way above and beyond what pilot projects have already shown.

Register for the informational webinar taking place on Wednesday, October 7

Click here to learn more about the opportunity and how to apply https://morethanmedicine.org/

Register for Webinar

Our Approach to Grantmaking

Our grantmaking is guided by three principles:

1) Protecting the core
2) Solving big problems
3) Inventing the future San Diego deserves

We support and partner with the organizations making a difference in San Diego County in the areas of arts and culture, youth success, health & well-being, and medical research.

Guided by our three principles, we also fund strategic priority areas: Balboa Park, the Tijuana River Valley, revitalizing downtown, and uplifting nonprofit journalism.

Grantmaking Areas

Arts & Culture

Arts & culture play a vital role in creating social cohesion, economic opportunities, and a sense of belonging in San Diego.

Youth Success

The Prebys Foundation is committed to ensuring all San Diego youth are healthy, engaged, and prepared for the future. 

Medical Research

Fostering a more collaborative, equitable, and innovative medical research system in San Diego. 

Health & Well-Being

Improving access to quality mental and physical healthcare for everyone.


Strategic Priority Areas

Downtown Revitalization

Reimagined as a welcoming civic and cultural district, the Downtown Civic Center can serve as a place where San Diegans live, learn, gather, create, and feel a stronger sense of belonging.

Tijuana River Pollution Crisis

Everyone deserves clean water, safe beaches, healthy air, and an environment where communities can thrive. Prebys supports community leaders, researchers, advocates, and public agencies working together to advance permanent solutions. 

Healthy Civil Society

San Diegan should have access to trustworthy information, meaningful opportunities to participate in civic life, and confidence that the issues shaping their future are being reported with independence, rigor, and relevance.

Balboa Park

The crown jewel of San Diego, home to museums, the world famous San Diego Zoo, restaurants, gardens, and a central hub of creativity and culture, is an invaluable resource that should be preserved and accessible to all San Diegans and visitors to our beautiful region. 


Supporting Nonprofits Beyond the Grant

Prebys invests in San Diego’s nonprofit community beyond grantmaking. 

We strengthen the organizations, leaders, and systems that help our region thrive — because a healthy, sustainable nonprofit sector is essential to creating lasting impact.

Through BRIDGE, we invest in nonprofit leadership and capacity building. Through partnerships with the Nonprofit Institute and the Nonprofit Sustainability Initiative, we help make valuable resources, tools, and support available to nonprofit organizations across the region. And through our support for advocacy and sector-wide efforts, we work to advance policies and practices that strengthen the nonprofit ecosystem.

Together, these investments help build a stronger, more resilient nonprofit community — one better equipped to serve San Diegans today and for generations to come.